Olympus LDL Cholesterol Reagent Beckman Coulter OSR6196

Description

Beckman Coulter OSR6196 Olympus LDL Cholesterol Reagent for LDL Test / lipid panel Specifications:

• Manufacturer: Beckman Coulter OSR6196
• Country of Origin: Japan
• Application: Reagent
• Number of Tests: 4 X 170 Tests
• Storage Requirements: Requires Refrigeration
• Test Name: Direct Low-Density Lipoprotein (LDL Test / lipid panel) Cholesterol
• Test Type: Cardiac / Lipids / General Chemistry
• UNSPSC Code: 41116004
• Volume: 4 X 30 mL, 4 X 10 mL
• Data Sheet
• Related products
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  • 2.Beckman Coulter OSR6195 Olympus HDL Cholesterol Reagent
  • 3.Beckman Coulter OSR6116 Olympus Cholesterol Reagent

Beckman Coulter OSR6196 Olympus LDL Cholesterol Reagent for LDL Test / lipid panel: Intended Use

Beckman Coulter OSR6196 Olympus LDL Cholesterol reagent, sometimes referred as a Low-Density Lipoprotein Cholesterol Reagent is used for the quantitative determination of LDL-Cholesterol concentrations in human serum and plasma on Beckman Coulter AU analyzers.

Understanding Beckman Coulter OSR6196 Olympus LDL Cholesterol Reagent for LDL Test / lipid panel

LDL-Cholesterol, also called Low-Density Lipoprotein Cholesterol, plays a significant role in causing coronary heart disease (CHD). In 1988, the National Cholesterol Education Program Adult Treatment Panel (NCEP-ATP) developed guidelines for diagnosing and treating hypercholesterolemia, with LDL-Cholesterol identified as the primary treatment target. The 2001 update of these guidelines (NCEP-ATP III) emphasized better risk identification and more aggressive cholesterol-lowering treatments.

Classification of LDL-Cholesterol Levels:

< 100 mg/dL: Optimal
100 – 129 mg/dL: Near optimal/above optimal
131 – 159 mg/dL: Borderline high
160 – 189 mg/dL: High
≥ 190 mg/dL: Very high

Methodology: Beckman Coulter OSR6196 Olympus LDL Cholesterol Reagent for LDL Test / lipid panel

The LDL-Cholesterol test uses a two-reagent homogenous system. It consists of two phases:

In the first phase, a special detergent solubilizes cholesterol from non-LDL lipoprotein particles. This cholesterol is then consumed by various enzymes to produce a colorless end product.
In the second phase, another detergent in the second reagent releases cholesterol from LDL lipoproteins. This cholesterol reacts with enzymes and a chromogen system to produce a blue color complex. This complex is measured at 540/660nm, and the increase in absorbance directly correlates with the LDL-C concentration in the sample.

A complete cholesterol test — also called a lipid panel or lipid profile — is a blood test that can measure the amount of cholesterol and triglycerides in your blood.

A cholesterol test / lipid panel can help determine your risk of the buildup of fatty deposits (plaques) in your arteries that can lead to narrowed or blocked arteries throughout your body (atherosclerosis).

A cholesterol test is an important tool. High cholesterol levels often are a significant risk factor for coronary artery disease.

Why cholesterol test / lipid panel is done?

High cholesterol usually causes no signs or symptoms. A complete cholesterol test is done to determine whether your cholesterol is high and to estimate your risk of heart attacks and other forms of heart disease and diseases of the blood vessels.

A complete cholesterol test includes the calculation of four types of fats in your blood:

• Total cholesterol. This is a sum of your blood’s cholesterol content.
• Low-density lipoprotein (LDL) cholesterol. This is called the “bad” cholesterol. Too much of it in your blood causes the buildup of fatty deposits (plaques) in your arteries (atherosclerosis), which reduces blood flow. These plaques sometimes rupture and can lead to a heart attack or stroke.
• High-density lipoprotein (HDL) cholesterol. This is called the “good” cholesterol because it helps carry away LDL cholesterol, thus keeping arteries open and your blood flowing more freely.
• Triglycerides. Triglycerides are a type of fat in the blood. When you eat, your body converts calories it doesn’t need into triglycerides, which are stored in fat cells. High triglyceride levels are associated with several factors, including being overweight, eating too many sweets or drinking too much alcohol, smoking, being sedentary, or having diabetes with elevated blood sugar levels.