Beckman Coulter OSR6152 Olympus TRF Reagent Transferrin Reagent
$1,992.63
Brand: Beckman CoulterTest Name: Transferrin
Article Number: OSR6152
- Description
Description
Beckman Coulter OSR6152 Olympus TRF Reagent (Transferrin Reagent trf chemistry) for Transferrin Test / TIBC Test Specifications:
- Manufacturer: Beckman Coulter OSR6152
- Country of Origin: Ireland
- Application: Reagent
- Number of Tests: 4 x 330
- Test Name: Transferrin Test / TIBC Test
- Test Type: Anemia Test / Specific Protein Test
- UNSPSC Code: 41116004
- Beckman Coulter OSR6152 Olympus TRF Reagent Data Sheet
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Intended Use: Beckman Coulter OSR6152 Olympus TRF Reagent (Transferrin Reagent trf chemistry) for Transferrin Test / TBIC Test
Beckman Coulter OSR6152 Olympus Transferrin reagent for the Transferrin quantitative determination in human serum on Beckman Coulter AU analyzers.
About Beckman Coulter OSR6152 Olympus TRF Reagent (Transferrin Reagent trf chemistry) for Transferrin Test / TBIC Test:
Iron in plasma is bound to the transport protein transferrin. Transferrin is responsible for 50% to 70% of the iron binding capacity of serum.
TRF has two iron-binding sites and is largely, but not exclusively, synthesized by the liver.
Transferrin levels rise with iron deficiency and fall in cases of iron overload. An increase in transferrin is seen in iron deficiency anemia. It may also be increased late in pregnancy and in women on oral contraceptives. It is decreased in conditions associated with increased protein loss, such as nephrotic syndrome, chronic renal failure, severe burns, and protein-deficiency states and in severe liver disease. Transferrin is a negative acute-phase protein and will be decreased during any inflammatory state or severe illness.
Methodology: Beckman Coulter OSR6152 Olympus TRF Reagent (Transferrin Reagent trf chemistry) for Transferrin Test / TBIC Test
Immune complexes formed in solution scatter light in proportion to their size, shape and concentration. Turbidimeters measure the reduction of incident light due to reflection, absorption, or scatter.
In the Anemia Test / Specific Protein Test procedure, the measurement of the decrease in light transmitted (increase in absorbance) through particles suspended in solution as a result of complexes formed during the antigen-antibody reaction, is the basis of this assay.
What is a Transferrin Test / TBIC Test?
A TIBC test (total iron-binding capacity) is a blood test that measures your blood’s ability (capacity) to attach (bind) to iron and carry it throughout your body. Healthcare providers use it to help diagnose iron-deficiency anemia and other iron metabolism conditions.
More specifically, a TIBC test shows the amount of transferrin in your blood. Transferrin is a protein your liver makes that regulates the absorption of iron into your blood.
Your body needs iron to make healthy red blood cells. Red blood cells carry oxygen from your lungs to the rest of your body. Iron is also important for healthy muscles, bone marrow and organ function.
Is TIBC test the same as ferritin test?
TIBC test and ferritin test are related tests, but they’re distinct.
A ferritin test measures the level of ferritin — a protein that stores iron inside your cells. While a TIBC test measures how your body transports iron via transferrin, a ferritin test measures how much iron your body stores. Ferritin is a better marker to assess iron deficiency.
When TIBC test is required?
Healthcare providers mainly order TIBC tests to diagnose conditions related to issues with iron. You could have too little iron in your body (iron-deficiency anemia) or too much (hemochromatosis).
A TIBC test is often part of an iron panel, which may also include the following tests:
- Fasting iron blood test.
- Percentage transferrin saturation or iron saturation.
- Ferritin blood test.
Providers may also use TIBC tests to monitor iron-related conditions.
