Olympus Lactate Reagent, Beckman Coulter OSR6193

Description

Beckman Coulter OSR6193 Olympus Lactate Reagent (beckman coulter lactate reagent for Lactate test) Specifications:

• Manufacturer: Beckman Coulter OSR6193
• Country of Origin: Italy
• Application: Reagent
• Number of Tests: 4 X 60 Tests
• Test Name: Lactate test
• Test Type: General Chemistry
• UNSPSC Code: 41116004
• Data Sheet
• Related Products:
  • Beckman Coulter OSR6127 Olympus LDH Reagent (Olympus Lactate Dehydogenase)

Intended Use Olympus Lactate Reagent (beckman coulter lactate reagent for Lactate test)

Beckman Coulter OSR6193 Olympus Lactate reagent for the quantitative determination of L-Lactate in human plasma and cerebrospinal fluid (CSF) on Beckman Coulter AU analyzers.

About Beckman Coulter OSR6193 Olympus Lactate Reagent (beckman coulter lactate reagent for Lactate test)

L-lactate is the end product of anaerobic glycolysis. It is derived predominantly from white skeletal muscle, brain, skin, renal medulla and erythrocytes. Lactate dehydrogenase catalyses the reduction of pyruvate to lactate.

There are two major clinical settings in which lactic acidosis occur:

(1) Conditions associated with hypoxia e.g. shock, congestive heart failure, myocardial infarction, blood loss and pulmonary edema.

(2) Metabolic or drug/toxin related disorders. Examples of metabolic disorders include diabetes mellitus, hepatic disease and neoplasia.

Congenital metabolic disorders include type I glycogen storage disease. Examples of drugs/toxins which give rise to elevated lactate are methanol, ethanol, epinephrine and acetaminophen.

L-lactate levels in CSF will generally mirror those in blood/plasma. However, increased lactate levels in CSF in the absence of increased blood/plasma lactate concentration have been reported in cases of bacterial meningitis, cerebral hypoxia, ischemia and in certain inborn errors of metabolism e.g. pyruvate dehydrogenase deficiency, mitochondrial myopathies and biotinidase deficiency.

Methodology: Beckman Coulter OSR6193 Olympus Lactate Reagent for Lactate test

L-lactate is oxidized to pyruvate and hydrogen peroxide by lactate oxidase (LOD). A colored product is produced by the reaction of peroxidase (POD), hydrogen peroxide, 4 -aminoantipyrine and a hydrogen donor (TOOS). The colored product is measured photometrically. The color intensity is proportional to the concentration of lactate in the sample under examination.

Beckman Coulter OSR6193 Olympus Lactate Reagent and Lactic Acid Blood Test levels

It’s a test that measures the amount of lactic acid (also called “lactate”) in your blood.

This acid is made in muscle cells and red blood cells. It forms when your body turns food into energy. Your body relies on this energy when its oxygen levels are low. Oxygen levels might drop during an intense workout or when you have an infection or disease. Once you finish your workout or recover from the illness, your lactic acid level tends to go back to normal.

But sometimes, it doesn’t.

What Is Lactic Acid?

Lactic acid is a chemical made by the body when it breaks down carbohydrates or glucose (stored energy) to use for fuel. It is produced by your cells when you use more oxygen than normal, such as during a strenuous workout. This happens most often in the muscles and blood cells but can occur anywhere in the body.

What does lactic acid do in the body?

When your body doesn’t have enough oxygen available to fuel its cells, it breaks down glucose to use as energy instead. This process creates lactic acid in the blood. Normally, the kidneys and liver filter out excess lactic acid and turn it back into glucose, which can be used as energy in the future. Lactic acid also spurs your immune system to repair and protect the body.