In Stock

Beckman Coulter OSR6286 Olympus Iron Reagent, 4 x 970 Tests


Brand: Beckman Coulter
Manufacturer SKU: OSR6286
Analyzer Type: Chemistry Analyzer
Analyzer Series: AU Analyzer Series
Test Type: General Chemistry
Test Name: Iron
SKU: OSR6286 Category:


Beckman Coulter OSR6286 Olympus Iron Reagent (Iron Test) Specifications:

Beckman Coulter OSR6286 Olympus Iron Reagent (Iron Test): Intended Use

Beckman Coulter OSR6286 Olympus Iron Reagent for the quantitative determination of Iron in human serum on Beckman Coulter AU analyzers.

Understanding Iron Measurements

Iron measurements are essential in diagnosing and treating diseases like iron deficiency anemia, hemochromatosis, and chronic renal disease. Transferrin, a protein in the serum, carries most of the iron in the blood.

Beckman Coulter OSR6286 Olympus Iron Reagent (Iron Test) Methodology

In 1954, Schade et al. introduced a method for directly determining serum iron levels. This involved incubating serum with a phosphate buffer, ascorbic acid, and terpyridine. In 1966, Goodwin proposed a similar method using an acetate buffer and bathophenanthroline, which improved accuracy by reducing random iron contamination and enhancing color development.

The Beckman Coulter method builds upon these techniques, utilizing TPTZ (2,4,6-Tri-(2-pyridyl)-5-triazine) as the chromogen. In an acidic environment, transferrin-bound iron releases as ferric ions, which are then reduced to the ferrous state using hydrochloric acid and sodium ascorbate. The ferrous ions react with TPTZ to form a blue complex, measurable at 600/800 nm. The increase in absorbance directly correlates with the amount of transferrin-bound iron.

Beckman Coulter OSR6286 Olympus Iron Reagent (Iron Test)
Beckman Coulter OSR6286 Olympus Iron Reagent (Iron Test)
What is iron test?
Beckman Coulter OSR6286 Olympus Iron Reagent Iron Test | JIT4You Clinical Lab Consumables
Beckman Coulter OSR6286 Olympus Iron Reagent Iron Test

Iron tests measure different substances in the blood to check iron levels in your body. Iron is a mineral that your body needs for growth and development. Your body uses iron to make hemoglobin, a protein in red blood cells. It carries oxygen from the lungs to all parts of the body, Iron is also important for healthy muscles, bone marrow, and organ function. Your body also needs iron to make some hormones.

You get iron from eating food or taking supplements. There are iron-only supplements, but many multivitamin/mineral supplements also contain iron.



Potential cases with Iron deficiency

Most people in the United States get enough iron. However, certain people may be more likely to have trouble getting enough iron. For example, those who:

The amount of iron you need each day depends on your age, your sex, and whether you consume a mostly plant-based diet. Iron levels that are too low or too high can cause health concerns. For example, not having enough iron in your body is the most common cause of anemia. Anemia is a condition in which your blood has a lower-than-normal amount of red blood cells.

The amount of iron in your blood varies throughout the day and may be higher in the morning.

There are different types of iron tests. You may just have one type of test. But in some cases, your health care provider might order several different iron tests to understand your results better. The different types of iron tests include:

  • Serum iron test, which measures the amount of iron in the blood
  • Transferrin test, which measures transferrin, a protein that moves iron throughout the body
  • Total iron-binding capacity (TIBC), which measures how well iron attaches to transferrin and other proteins in the blood
  • Ferritin blood test, which measures how much iron is stored in the body

Other names: Serum Iron, Serum Fe, Ferritin Test, Serum Ferritin

What are they used for?

Iron tests are most often used to:

  • Check if the iron levels in your blood are too low, a sign of anemia. But not all people who have low iron levels have anemia.
  • Diagnose different types of anemia.
  • Check if the iron levels in your blood are too high, which could be a sign of hemochromatosis (also called iron overload). This condition causes too much iron to build up in your body. It can be inherited (passed down through families) or be caused by another health condition.
  • Measure the amount of iron stored in your liver to check for liver disease.
  • Check for restless legs syndrome (tingling or burning feelings in your legs).
  • Check for adult Still disease, also called adult-onset Still disease or AOSD. This is not a common condition. Symptoms include a high ferritin level, joint pain, fever, and a rash.
  • See if treatments for iron deficiency (low iron levels) or excess iron (high iron levels) are working.