Beckman Coulter 33005 Access Vitamin B12 Calibrator (S0-S5)
$183.40
Analyzer Series: Access Analyzer SeriesBrand: Beckman Coulter
Manufacturer SKU: 33005
Package Size: 6 x 4.0 mL
Test Name: Vitamin B12
Analyzer Type: Hematology Analayzer
- Description
Description
Beckman Coulter 33005 Access Vitamin B12 Calibrator (B12 Test) Specifications
- Brand: Access
- Manufacturer: Beckman Coulter 33005
- Country of Origin: United States
- Application: Access Calibrator
- Storage Requirements: Requires Refrigeration
- Test Name: Vitamin B12
- Volume : 6 X 4 mL
- Beckman Coulter Calibrator Vitamin B12 Data Sheet
- Related products
Beckman Coulter 33005 Access Vitamin B12 Calibrator (B12 Test): INTENDED USE
The Access Vitamin B12 Calibrator are intended to calibrate the Access Vitamin B12 assay for the quantitative determination of vitamin B12 levels in human serum and plasma (heparin) using the Access Immunoassay Systems.
Beckman Coulter 33005 Access Vitamin B12 Calibrator (B12 Test): SUMMARY AND EXPLANATION
Quantitative assay calibration is the process by which samples with known analyte concentrations (i.e., assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. This mathematical relationship, or calibration curve, is used to convert RLU (Relative Light Unit) measurements of patient samples to specific quantitative analyte concentrations.
Vitamin B12 level
Cobalamin test; Pernicious anemia – vitamin B12 level. The vitamin B12 level is a blood test that measures how much vitamin B12 is in your blood.
Why the Test is Performed
This test is most often done when other blood tests suggest a condition called megaloblastic anemia. Pernicious anemia is a form of megaloblastic anemia caused by poor vitamin B12 absorption. This can occur when the stomach makes less of the substance the body needs to properly absorb vitamin B12.
Your provider may also recommend a vitamin B12 test if you have certain nervous system symptoms. A low level of B12 can cause numbness or tingling in the arms and legs, weakness, and loss of balance.
Other conditions for which the test may be done include:
- Sudden severe confusion (delirium)
- Loss of brain function (dementia)
- Dementia due to metabolic causes
- Nerve abnormalities, such as peripheral neuropathy
B12 Test Normal Results
Normal values are 160 to 950 picograms per milliliter (pg/mL), or 118 to 701 picomoles per liter (pmol/L).
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples. Talk to your provider about what your specific test results mean.
What Abnormal Results Mean
Values of less than 160 pg/mL (118 pmol/L) are a possible sign of a vitamin B12 deficiency. People with this deficiency are likely to have or develop symptoms.
Older adults with a vitamin B12 level less than 100 pg/mL (74 pmol/L) may also have symptoms. Deficiency should be confirmed by checking the level of a substance in the blood called methylmalonic acid. A high level indicates a true B12 deficiency.
Causes of vitamin B12 deficiency include:
- Not enough vitamin B12 in diet (rare, except with a strict vegetarian diet)
- Diseases that cause malabsorption (for example, celiac disease and Crohn disease)
- Lack of intrinsic factor, a protein that helps the intestine absorb vitamin B12
- Above normal heat production (for example, with hyperthyroidism)
- Pregnancy
An increased vitamin B12 level is uncommon. Usually, excess vitamin B12 is removed in the urine.
Conditions that can increase B12 level include:
- Liver disease (such as cirrhosis or hepatitis)
- Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)
