Beckman Coulter 33535 Access Prolactin Calibrator S0 S5|JIT4You | JIT4You Clinical Lab Consumables
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Access Prolactin Calibrator (S0-S5) Beckman Coulter 33535

Brand:Beckman Coulter

$169.00

Brand: Beckman Coulter
Article Number: 33535
Package Size: 2.5 mL
Test Name: Prolactin
SKU: 33535 Category:

Description

Beckman Coulter 33535 Access Prolactin Calibrator (S0-S5) for Prolactin Test / PRL Test Specifications

Beckman Coulter 33535 Access Prolactin Calibrator (S0-S5) for Prolactin Test / PRL Test INTENDED USE:

The Access-Prolactin Calibrators are part of the Prolactin Test, intended to calibrate the Access Prolactin assay for the quantitative determination of prolactin (PRL) levels in human serum and plasma (heparin) using the Access Immunoassay Systems.

Beckman Coulter 33535 Access Prolactin Calibrator (S0-S5) for Prolactin Test / PRL Test: SUMMARY AND EXPLANATION

Quantitative assay calibration is the process by which samples with known analyte concentrations (i.e., assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. This mathematical relationship, or calibration curve, is used to convert RLU (Relative Light Unit) measurements of patient samples to specific quantitative analyte concentrations.

A prolactin test (PRL Test) measures how much of a hormone called prolactin you have in your blood. The hormone is made in your pituitary gland, which is located just below your brain.

When people are pregnant or have just given birth, their prolactin levels increase so they can make breast milk. But it’s possible to have high prolactin levels if you’re not pregnant. Anyone can have high prolactin levels. When people are pregnant or have just given birth, their prolactin levels increase so they can make breast milk. But it’s possible to have high prolactin levels if you’re not pregnant. A prolactin blood test measures how much prolactin you have in your blood (Photo credit: E+/Getty Images)

Prolactin helps your body work properly. It supports many actions and processes that happen in the body every day, including the creation of blood vessels.

Prolactin is especially important for pregnant people. It makes lactation and milk production possible.

People assigned male at birth have lower levels of prolactin.

How is it made?

Many hormones, including prolactin, come from the pituitary gland. Dopamine, a neurotransmitter, and estrogen, a hormone, signal to the pituitary gland that it’s time to produce and distribute prolactin.

Other areas of the body that create prolactin include the mammary glands, uterus, immune system, and even the central nervous system.

How it works in the body

Prolactin encourages mammary glands in the breast to grow and develop. It nurtures breast tissue in the mammary glands called “mammary alveoli,” where milk is produced. Combined with estrogen and progesterone, prolactin prompts the breasts to create milk.

Prolactin also helps ensure the breast milk contains all the necessary nutrition for a baby, including lipids for energy, casein for protein, and lactose for carbohydrates. Prolactin helps maintain the milk supply for feeding an infant. It rises when the baby feeds at the breast. If you deliver a baby but decide not to breastfeed, your prolactin will typically fall within 2 weeks to its level before your pregnancy.

Beckman Coulter 33535 Access Prolactin Calibrator S0 S5 for Prolactin Test PRL Test | JIT4You Clinical Lab Consumables
Beckman Coulter 33535 Access Prolactin Calibrator S0 S5 for Prolactin Test PRL Test

The normal range for prolactin in your blood is:

  • Male/assigned male at birth: less than 20 nanograms per milliliter (ng/mL)

  • Non-pregnant female/assigned female at birth: less than 25 ng/mL

  • Pregnant people: 80 to 400 ng/mL

What’s considered normal may be different depending on which lab your doctor uses.

If your value falls outside the normal range, this doesn’t automatically mean you have a problem. Sometimes the levels can be higher if you’ve eaten or were under a lot of stress when you got your blood test.

High levels of prolactin, also known as hyperprolactinemia, can cause infertility in women. Periods can become irregular.

If your levels are very high — up to 1,000 times the upper limit of what’s considered normal — this could be a sign that you have prolactinoma — a tumor in your pituitary gland. This tumor is not cancer, and it is usually treated with medicine. In this case, your doctor may want you to get an MRI, which uses radio waves to put together a detailed image of your brain. It will show whether there’s a mass near your pituitary gland and how big it is.

Normally, men and nonpregnant women have just traces of prolactin in their blood. When you have high levels, this could be caused by:

  • Prolactinoma (a benign tumor in your pituitary gland that produces too much prolactin)
  • Diseases affecting the hypothalamus (the part of the brain that controls the pituitary gland)
  • Anorexia (an eating disorder)
  • Drugs that are used to treat depression, psychosis, high blood pressure, nausea, and vomiting, pain relievers with opioids, and birth control pills
  • Chest injury or irritation (for example, scars, shingles, or even a bra that’s too tight)