Beckman Coulter 387647 Access BR Monitor Calibrator (S0-S5)
$189.63
Brand: Beckman CoulterTest Type: Antigen (Cancer)
Test Name: CA 15-3
Manufacturer SKU: 387647
Analyzer Type: Hematology Analayzer
Analyzer Series: Access Analyzer Series
- Description
Description
Beckman Coulter 387647 Access BR Monitor Calibrator (CA15-3 Test) Specifications:
- Brand: Access BR Monitor
- Manufacturer: Beckman Coulter 387647
- Country of Origin: United States
- Application: Calibrator For Use With: For Access SystemLevels: Level S0, S1, S2, S3, S4 S5
- Test Name: CA15-3 Test
- Test Type: Cancer
- Volume: 6 X 1.5 mL
- Related Products
- Access BR Monitor Calibrator Beckman Coulter 387647 Data Sheet
Beckman Coulter 387647 Access BR Monitor Calibrator (CA15-3 Test): INTENDED USE
The Access BR-Monitor Calibrator are intended to calibrate the Access BR-Monitor assay for the quantitative determination of CA 15-3 antigen levels in human serum and plasma using the Access Immunoassay Systems.
Beckman Coulter 387647 Access BR Monitor Calibrator (CA15-3 Test): SUMMARY AND EXPLANATION
Quantitative assay calibration is the process by which samples with known analyte concentrations (i.e., assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. This mathematical relationship, or calibration curve, is used to convert RLU (Relative Light Unit) measurements of patient samples to specific quantitative analyte concentrations.
Cancer antigen 15-3 (CA15-3) is a protein made by a variety of cells, particularly breast cancer cells. The protein moves into the blood, where it can be measured.
CA 15-3 levels are higher than normal in most women with breast cancer that has spread to other parts of the body (called metastatic breast cancer). Not all types of breast cancer will cause CA 15-3 levels to rise, as some types of cancer cells don’t over-produce the antigen.
CA15-3 is a tumour marker. It is used to check how breast cancer treatment is working and look for cancer that has come back, or recurred, after treatment.
If you are diagnosed with breast cancer that has spread to other parts of the body, or metastasized, you may have this test, along with other tests such as hormone receptor testing and HER2 status testing.
CA15-3 is not measured for early stage breast cancer because the levels of this protein are rarely higher than normal at this stage.
What CA15-3 test results mean?
CA15-3 levels can be higher than normal with cancerous and non-cancerous conditions. CA15-3 is most often increased in breast cancer that has spread to other parts of the body.
In general, the higher the level of CA15-3 in the blood, the more cancer there is in the body. The levels are highest when breast cancer has spread to the bones, the liver or both. If the level of CA 15-3 goes down or returns to normal, it may mean that treatment is working. If levels increase over time, it may mean that the cancer is not responding well to treatment, is still growing or is coming back (recurring).
CA 15-3 may be higher than normal in cancer of the lung, pancreas, ovary and prostate, but these levels are not as high as with breast cancer.
Non-cancerous conditions that increase CA 15-3 include endometriosis, pelvic inflammatory disease and liver disease. It can also be increased during pregnancy. With these conditions, CA 15-3 levels usually only go so high. They don’t usually keep climbing over time.
