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Beckman Coulter 33710 Access Digoxin Reagent, 100 Determinations

$343.20

Analyzer Series: Access Analyzer Series
Brand: Beckman Coulter
Manufacturer SKU: 33710
Package Size: 2 x 50 Tests
Test Type: Therapeutic Drug Monitoring
Test Name: Digoxin
Analyzer Type: Hematology Analayzer
SKU: 33710 Category:

Description

Beckman Coulter 33710 Access Digoxin Reagent Specifications

  • Brand: Access
  • Manufacturer: Beckman Coulter 33710
  • Country of Origin: United States
  • Application: Reagent
  • Number of Tests: 100 Tests
  • Test Name: Digoxin Test
  • Test Type: Therapeutic Drug Monitoring
  • Volume: 2 X 50 mL
Access Digoxin Reagent INTENDED USE:

Within the Digoxin Test, the Access Digoxin assay is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of digoxin levels in human serum using the Access Immunoassay Systems.

Access Digoxin Reagent SUMMARY AND EXPLANATION:

Digoxin is a potent, cardiac glycoside isolated from the leaves of Digitalis lanta. This glycoside is a widely prescribed drug used in the treatment of congestive heart failure, atrial fibrillation, atrial flutter, supraventricular tachycardia, and other cardiac disorders. Treatment with digoxin results in more effective cardiac contractility, decrease in conduction velocity, and a slowing of the heart rate.The therapeutic range for digoxin is narrow.

Desired effects become exaggerated with administration of an excess of digoxin leading to conditions difficult to distinguish from the original cardiac symptoms. Coupled with the narrow therapeutic to toxic range is a considerable variability in patient response to the same dose. In different patients identical doses of digoxin result in different serum levels mainly due to individual variation in myocardial sensitivity, absorption, diet, and excretion of the drug.

The variability in bioavailability of different drug formulations and interactions with other drugs, particularly drugs affecting the electrolyte balance such as diuretics, also affect individual patient responses. Measuring a serum sample drawn 6-8 hours after the administration of digoxin allows for equilibration of serum and tissue digoxin levels. Monitoring digoxin levels can assist the physician in adjusting digoxin dosage.

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