Beckman Coulter 33710 Access Digoxin Reagent, 100 Determinations

Description

Beckman Coulter 33710 Access Digoxin Reagent (Digoxin Test) Specifications:

• Brand: Access
• Manufacturer: Beckman Coulter 33710
• Country of Origin: United States
• Application: Access Digoxin Reagent
• Number of Tests: 100 Tests
• Test Name: Digoxin Test
• Test Type: Therapeutic Drug Monitoring
• Volume: 2 X 50 mL

Beckman Coulter 33710 Access Digoxin Reagent INTENDED USE:

Within the Digoxin Test, the Access Digoxin reagent assay is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of digoxin levels in human serum using the Access Immunoassay Systems.

Beckman Coulter 33710 Access Digoxin Reagent SUMMARY AND EXPLANATION:

Digoxin is a potent, cardiac glycoside isolated from the leaves of Digitalis lanta. This glycoside is a widely prescribed drug used in the treatment of congestive heart failure, atrial fibrillation, atrial flutter, supraventricular tachycardia, and other cardiac disorders. Treatment with digoxin results in more effective cardiac contractility, decrease in conduction velocity, and a slowing of the heart rate.The therapeutic range for digoxin is narrow.

Beckman Coulter 33710 Access Digoxin Reagent: Desired Effect

Desired effects become exaggerated with administration of an excess of digoxin leading to conditions difficult to distinguish from the original cardiac symptoms. Coupled with the narrow therapeutic to toxic range is a considerable variability in patient response to the same dose. In different patients identical doses of digoxin result in different serum levels mainly due to individual variation in myocardial sensitivity, absorption, diet, and excretion of the drug.

The variability in bioavailability of different drug formulations and interactions with other drugs, particularly drugs affecting the electrolyte balance such as diuretics, also affect individual patient responses. Measuring a serum sample drawn 6-8 hours after the administration of digoxin allows for equilibration of serum and tissue digoxin levels. Monitoring digoxin levels can assist the physician in adjusting digoxin dosage.

More about Beckman Coulter 33710 Access Digoxin Reagent and Digoxin test:

A digoxin test checks how much digoxin you have in your blood. Digoxin is a type of medicine called a cardiac glycoside. It is used to treat certain heart problems, although much less often than in the past.

• Alternative Names: Heart failure – digoxin test
• How the Digoxin Test is Performed: A blood sample is needed.
• Why the Digoxin Test is Performed?
  • The main purpose of the Digoxin test is to determine the best dosage of digoxin and prevent side effects. It is important to monitor the level of digitalis medicines such as digoxin. That is because the difference between a safe treatment level and a harmful level is small.
• What consider normal Digoxin Test results?
  • In general, normal values range from 0.5 to 1.9 nanograms per milliliter of blood. But the right level for some people may vary depending on the situation.

The examples above are common measurements for results of these tests. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples.

• What Abnormal Digoxin Test results Mean
  • Abnormal results may mean you are getting too little or too much digoxin. A very high value could mean that you have or are likely to develop a digoxin overdose (toxicity).

Useful Links

Beckman Coulter 33715 Access Digoxin Calibrator (S0-S5)