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Beckman Coulter B63284 Access TSH Stimulating Hormone (3rd IS) 2 x 100 Determinations

$307.00

Brand: Beckman Coulter
Manufacturer SKU: B63284
Test Type: Thyroid / Metabolic Assay
Analyzer Type: Hematology Analayzer
Analyzer Series: Access Analyzer Series
Test Name: Thyroid Stimulating Hormone (TSH)
SKU: B63284 Category:

Description

Beckman Coulter B63284 Access TSH Stimulating Hormone (3rd IS) for TSH test Specifications:

  • Brand: UniCel® DxL
  • Manufacturer: Beckman Coulter B63284
  • Country of Origin: United States
  • Application: Hematology Reagent Access TSH
  • For Use With: For use with Access Immunoassay Systems
  • Number of Tests: 100 Tests
  • Sample Type: Serum / Plasma Sample
  • Storage Requirements: Requires Refrigeration
  • Test Name: Thyroid Stimulating Hormone (TSH Test)
  • Test Type: Thyroid / Metabolic Assay
  • Volume: 2 Packs
INTENDED USE Hematology Thyroid Stimulating Hormone Access TSH Reagent

The Beckman Coulter B63284 Access TSH (3rd IS) Hematology Reagent assay is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of human thyroid-stimulating hormone (thyrotropin, TSH, hTSH) levels in human serum and plasma using the Access Immunoassay Systems. This assay is capable of providing 3rd generation TSH results.

Beckman Coulter B63284, Hematology Thyroid Stimulating Hormone Access TSH Reagent SUMMARY AND EXPLANATION

Human thyroid stimulating hormone is a glycoprotein hormone consisting of two noncovalently-bound subunits: an α subunit, which is nearly identical to the α subunits of human luteinizing hormone (hLH), human follicle-stimulating hormone (hFSH), and human chorionic gonadotropin (hCG), and a β subunit, which is responsible for immunological and biological specificity.

TSH, released from the anterior pituitary, is the principal regulator of thyroid function, stimulating the synthesis and release of thyroid hormones thyroxine (T4) and triiodothyronine (T3). T3 and T4 regulate biochemical processes that are essential for normal metabolism. The synthesis and secretion of TSH is stimulated by thyrotropin-releasing hormone

(TRH), which is produced by the hypothalamus in response to low levels of circulating T3 and T4. In contrast, elevated levels of T3 and T4 suppress the production of TSH. Collectively, this negative feedback system is referred to as the hypothalamic-pituitary-thyroid axis. Any alteration in the function of this axis can influence the levels of TSH, T4, and T3 in circulation.

The principal clinical use for TSH measurement is for the assessment of thyroid status. TSH is measured in conjunction with thyroid hormones or antibodies to: 1) detect or exclude hypothyroidism or hyperthyroidism; 2) monitor T4 replacement treatment in hypothyroidism or antithyroid treatment in hyperthyroidism; 3) monitor TSH suppression in thyroid cancer patients on thyroxine therapy; and 4) assess the response to TRH stimulation testing.

Reference ranges for TSH may vary, depending on the method of analysis, and do not necessarily equate to cut-offs for diagnosing thyroid dysfunction.

As methods achieving third-generation sensitivity have become available, TSH measurements are also used to identify subclinical or latent hypothyroidism or hyperthyroidism. Third generation methods for TSH measurement are defined as achieving a functional sensitivity of 0.01-0.02 µIU/mL (mIU/L) with an interassay %CV ≤ 20%. Clinical laboratories may use these more sensitive and precise methods to distinguish different levels of TSH suppression associated with Graves’ disease and subclinical hyperthyroidism and to assist in the diagnosis of gestational and postpartum thyroid diseases

Beckman Coulter B63284 Thyroid Stimulating Hormone and TSH Test
Beckman Coulter B63284 Access TSH Stimulating Hormone 3rd IS for TSH test | JIT4You Clinical Lab Consumables
Beckman Coulter B63284 Access TSH Stimulating Hormone 3rd IS for TSH test

TSH stands for thyroid stimulating hormone. A TSH test is a blood test that measures this hormone. TSH levels that are too high or too low may be a sign of a thyroid problem.

The thyroid is a small, butterfly-shaped gland in the front of your neck. Your thyroid makes hormones that control how your body uses energy. Thyroid hormones affect nearly every organ in your body, including your heart. They help control your weight, body temperature, muscle strength, and even your mood. If you don’t have enough thyroid hormones in your blood, many of your body functions slow down. If you have too much, many body functions speed up.

 

 

 

Your thyroid is controlled by a gland in your brain, called the pituitary gland. The pituitary gland makes thyroid stimulating hormone (TSH). TSH tells your thyroid how much thyroid hormone it needs to make.

If the thyroid hormone levels in your blood are too low, your pituitary gland makes larger amounts of TSH to tell your thyroid to work harder. If your thyroid hormone levels are too high, the pituitary gland makes little or no TSH. By measuring TSH levels in your blood, you can find out if your thyroid is making the right level of hormones.

Other names: thyrotropin test

Beckman Coulter B63284: What is it used for?

A TSH test is used to find out how well your thyroid is working. It can tell if you have hyperthyroidism (too much thyroid hormone) or hypothyroidism (too little thyroid hormone) in your blood. But a TSH test can’t show what is causing a thyroid problem.

If you take prescription thyroid hormone medicine because of hypothyroidism or because you had your thyroid removed, you’ll have regular TSH tests to check your thyroid hormone levels. TSH tests are also used to monitor your thyroid hormone levels after treatment for hyperthyroidism.

Useful Links

TSH Calibrator: Beckman Coulter B63285 Access TSH Calibrator (3rd IS) S0-S5