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Beckman Coulter OSR6159 Olympus C3 Reagent (Complement 3 Reagent)


Intended Use

Beckman Coulter OSR6159 Olympus C3 Reagent, also called Complement 3 Reagent for the quantitative determination of Complement 3 (C3) in human serum on Beckman Coulter AU analyzers.

Brand: Beckman Coulter
Manufacturer SKU: OSR6159
Analyzer Type: Chemistry Analyzer
Analyzer Series: AU Analyzer Series
Test Type: Specific Protein Test
Test Name: Complement C3
SKU: OSR6159 Category:


Beckman Coulter OSR6159 Olympus C3 Reagent (C3 complement test) Specifications:

  • Manufacturer: Beckman Coulter OSR6159
  • Country of Origin: Ireland
  • Application: Reagent
  • For Use With: For AU Clinical Chemistry Systems
  • Number of Tests: 4 X 260 Tests
  • Sample Type: complement 3 serum Sample
  • Test Name: C3 complement test
  • Test Type: Immunochemistry / Specific Protein Test
  • UNSPSC Code: 41116010
  • Volume: 4 X 10 mL, 4 X 8 mL
  • Data Sheet
Understanding Beckman Coulter OSR6159 Olympus C3 Reagent (C3 complement test):

The Complement system, which consists of a series of circulating blood proteins, serves as crucial mediators of the inflammatory response. C3, comprising approximately 70% of the total protein in the complement system, holds central importance in activating both the classical and alternate pathways. Consequently, measurements of this protein are invaluable in diagnosing immunologic disorders, particularly those associated with deficiencies of complement components.

Beckman Coulter OSR6159 Olympus C3 Reagent (C3 complement test) Methodology:

In this methodology, immune complexes formed in solution scatter light based on their size, shape, and concentration. Utilizing turbidimeters, the reduction of incident light caused by reflection, absorption, or scatter is measured. Specifically, the measurement focuses on the decrease in light transmitted (increase in absorbance) through suspended particles resulting from complexes formed during the antigen-antibody reaction. This forms the basis of this complement 3 serum, allowing for accurate analysis and diagnosis.

What is a C3 complement test?

A C3 complement blood test measures the levels of a specific type of protein in your blood (C3 proteins). As part of your immune system, C3 proteins destroy microbes (germs) that can make you sick. Sometimes, C3 proteins launch an attack against healthy cells by mistake.

The results of this blood test give your healthcare provider information about how your immune system is working. By measuring the amount of C3 proteins, your healthcare provider can diagnose infection, disease, immune deficiency and other health conditions, like autoimmune disorders. This test also helps your healthcare provider monitor treatment for autoimmune disease.

What is the C3 complement system?

C3 proteins are part of the complement system, which is part of your immune system. The complement system includes more than 30 different proteins. They work together in a sequence to protect you from infection and illness.

When your immune system identifies a harmful substance or recognizes signs of an infection, it activates a protein in the complement system to launch an attack. That protein activates another protein, which activates another and another. Healthcare providers call this process a complement cascade. The proteins, like C3, are consumed in this process.

Proteins in the complement system have many jobs, including:

  • Helping your immune system create antibodies (proteins that respond to specific germs) and making antibodies more effective.
  • Helping your body get rid of dead cells and other waste.
  • Neutralizing viruses (making them less harmful).
  • Recognizing and killing viruses, bacteria and other germs.
  • Working with other parts of the immune system to help them destroy bacteria.

Sometimes, complement proteins like C3 mistakenly attack tissues that aren’t dangerous. Autoimmune disorders cause the body to believe its own tissues are foreign and harmful. The complement system responds by making antibodies to fight its own tissues.

When is a C3 complement blood test performed?
Beckman Coulter OSR6159 Olympus C3 Reagent C3 complement test | JIT4You Clinical Lab Consumables
Beckman Coulter OSR6159 Olympus C3 Reagent C3 complement test

Your healthcare provider may order this test if you have:

  • Bacterial infections that don’t go away or keep coming back.
  • Edema (swelling) or inflammation.
  • Symptoms of an autoimmune disorder, like lupus.

Your healthcare provider might also recommend a C3 complement blood test to monitor:


Test Details: How does a C3 complement test work?

Your healthcare provider removes a sample of your blood through a vein in your arm. They send the sample to a lab to check the levels of C3 proteins in your blood.

The lab may also look at the levels of other proteins (such as C4 proteins) and see how they compare to the amount of C3 proteins. Your healthcare provider will contact you when the results are ready and explain what they mean.