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Beckman Coulter 37210 Access Hybritech free PSA Reagent, 100 Determinations

$566.70

Brand: Beckman Coulter
Manufacturer SKU: 37210
Analyzer Type: Hematology Analayzer
Analyzer Series: Access Analyzer Series, Synchron LXI Analyzer Series, UniCel DXI Analyzer Series
Test Type: Cancer Immunoassay
Test Name: Free Prostate-specific Antigen (PSA)
SKU: 37210 Category:

Description

Beckman Coulter 37210 Access Hybritech free PSA Reagent Specifications:

  • Brand: Access® Hybritech®
  • Manufacturer: Beckman Coulter 37210
  • Country of Origin: United States
  • Application: Free PSA Reagent
  • For Use With: For Synchron LXI, Unicel DXI, Access 2
  • Number of Tests: 2 X 50 Tests
  • Test Name: Free Prostate-specific Antigen (PSA)
  • Test Type: Cancer
Access Hybritech free PSA Reagent: INTENDED USE

The Access Hybritech free PSA assay is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of free prostate specific antigen (free PSA) in human serum using the Access Immunoassay Systems. Access Hybritech free PSA is intended to be used with Hybritech (total) PSA to calculate the ratio of free PSA to total PSA expressed as a percentage (percent free PSA). Percent free PSA as measured by the Hybritech assays is indicated foruse as an aid in distinguishing prostate cancer from benign prostatic conditions, when used in conjunction with Hybritech (total) PSA for prostate cancer detection in men aged 50 years and older with total PSA between 4 and 10 ng/mL with digital rectal examination findings that are not suspicious for cancer. Prostatic biopsy is required for diagnosis of cancer.

Access Hybritech free PSA Reagent: SUMMARY AND EXPLANATION

Prostate cancer is the most common type of cancer found in men in the United States, with an incidence of approximately

one case for every ten men. It is also the second leading cause of cancer deaths among American men.

Prostate-specific antigen was identified and purified by Wang and co-workers in 1979. PSA, a serine protease, is produced by the epithelial cells of the prostate, and is produced by both benign and malignant cells. Abnormalities in the prostate gland architecture resulting from trauma or disease can lead to “leakage” of PSA into the bloodstream.

PSA exists primarily as three forms in serum. One form of PSA is believed to be enveloped by the protease inhibitor, alpha-2 macroglobulin and has been shown to lack immunoreactivity. A second form is complexed to another protease inhibitor, alpha-1 antichymotrypsin (ACT). The third form of PSA is not complexed to a protease inhibitor, and is termed free PSA. The latter two forms are immunologically detectable in commercially available PSA assays and are referred to collectively as total PSA.

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