Beckman Coulter A31589 Access Toxo IgG Calibrator (S0-S5)

Description

Beckman Coulter A31589 Access Toxo IgG Calibrator (S0-S5), (Toxoplasmosis IgG / Toxoplasmosis IgM) Specifications:

• Brand: Access
• Manufacturer: Beckman Coulter A31589
• Country of Origin: France
• Application: Access Toxo IgG Calibrator
• Container Type: Vial
• Storage Requirements: Requires Refrigeration
• Test Name: Toxo IgG Test
• Volume : 6 X 1 mL
• Related Products
  • 1.Beckman Coulter A31588 Access Toxo IgG Reagent, 100 Determinations
  • 2.Beckman Coulter A31590 Access Toxo IgG QC (QC1-QC2)

Beckman Coulter A31589 Access Toxo IgG Calibrator (S0-S5), (Toxoplasmosis IgG / Toxoplasmosis IgM): INTENDED USE

The Access Toxo IgG Calibrators are intended to calibrate the Access Toxo-IgG assay for the qualitative and quantitative determination of IgG antibodies to Toxoplasma gondii in human serum using the Access Immunoassay Systems.

Beckman Coulter A31589 Access Toxo IgG Calibrator (S0-S5), (Toxoplasmosis IgG / Toxoplasmosis IgM): SUMMARY AND EXPLANATION

Quantitative assay calibration is the process by which samples with known analyte concentrations (i.e. assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. This mathematical relationship, or calibration curve, is used to convert RLU (Relative Light Unit) measurements of patient samples to specific quantitative analyte concentrations.

Toxoplasmosis IgG and Toxoplasmosis IgM

Toxoplasmosis is an infection caused by a parasite. The test detects antibodies produced in response to an old or recent infection by the parasite. During infection, the body first produces measurable IgM antibodies in the blood 1 to 2 weeks after infection. A few months later, IgM becomes undetectable and is replaced by IgG antibodies that will be present for the rest of the person’s life. IgM antibodies may reappear if the infection is reactivated or if the infection is chronic. Detection of toxoplasmosis is particularly important in pregnant women because of the high risk (30% to 40%) of transmitting the infection to the fetus. Fetal toxoplasmosis can lead to miscarriages, fetal death and numerous complications (mental retardation, blindness, deafness, etc.).

Negative IgM and IgG results indicate that the person has no immunity against toxoplasmosis and, if a woman becomes infected in early pregnancy, the parasite could be transmitted to the fetus. Positive IgG results indicate that the person is immunized and is not at risk of transmitting the infection to the fetus. If IgM results are also positive, the infection is recent. Negative IgG results with confirmed positive IgM results indicate a recent infection. Inconclusive results should be confirmed on a new specimen 3 weeks after the first test.