Beckman Coulter OSR6119 Olympus GGT Reagent R1 (4×310 tests)

Description

Beckman Coulter OSR6119 Olympus GGT Reagent R1 (Gamma Glutamyl Transferase Test / GGT Test) Specifications:

• Manufacturer: Beckman Coulter OSR6119
• Country of Origin: Ireland
• Application: Reagent, GGT Beckman Coulter
• Number of Tests: 4×310 Tests
• Storage Requirements: Requires Refrigeration
• Test Name: Gamma Glutamyl Transferase Test (GGT Test)
• Test Type: Hepatic / General Chemistry
• UNSPSC Code: 41116004
• Volume: R1 4x18ml, R2 4x18ml
• Beckman Coulter OSR6119 Olympus GGT Reagent R1 Data Sheet
• Related Products
  • Chemistry Reagents

Beckman Coulter OSR6119 Olympus GGT Reagent R1 (Gamma Glutamyl Transferase Test / GGT Test): Intended Use

OSR6119 Olympus GGT Reagent for the quantitative determination of Gamma-Glutamyltransferase (EC 2.3.2.2) activity in human serum on Beckman Coulter AU analyzers.

Understanding Beckman Coulter OSR6119 Olympus GGT Reagent R1 (Gamma Glutamyl Transferase Test / GGT Test):

GGT-Reagent is essential in diagnosing and treating liver diseases like alcoholic cirrhosis and liver tumors. Elevated levels of gamma-glutamyltransferase (GGT or GGTP) indicate liver issues, making it a crucial marker for various conditions.

Compared to other liver enzymes like alkaline phosphatase, GGT is more sensitive in detecting liver problems such as obstructive jaundice and cholangitis. It rises earlier and to higher levels, making it a reliable indicator.

While GGT elevation is common in liver diseases like hepatitis, it can also occur in conditions like chronic alcoholism, diabetes, and certain neurological disorders. However, normal GGT levels suggest skeletal rather than liver issues.

Beckman Coulter OSR6119 Olympus GGT Reagent R1 (Gamma Glutamyl Transferase Test / GGT Test): Methodology

The GGT Beckman coulter test follows the Szasz procedure, which involves the transfer of a gamma-glutamyl group. This transfer leads to the formation of 5-amino-2-nitrobenzoate, causing a change in absorbance at 410/480 nm. This change directly reflects the GGT activity in the sample.

What is gamma-glutamyl transferase (GGT)?

Gamma-glutamyl transferase (GGT), also known as gamma-glutamyl transpeptidase, is an enzyme that’s found throughout your body, though it mainly exists in your liver. An enzyme is a type of protein in a cell that acts as a catalyst and allows certain bodily processes to happen. There are thousands of enzymes throughout your body that have important functions.

What is a gamma-glutamyl transferase Test (GGT Test) ?

A gamma-glutamyl transferase (GGT) blood test measures the activity of GGT in your blood. GGT may leak into your bloodstream if your liver or bile duct is damaged, so having high levels of GGT in your blood may indicate liver disease or damage to your liver’s bile ducts. Bile ducts are tubes that carry bile (a fluid that’s important for digestion) in and out of your liver.

Your GGT Test levels can also rise from administration of foreign substances such as medications (like phenobarbital, phenytoin or warfarin) or alcohol.

GGT is typically the first liver enzyme to increase in your blood when any of your liver bile ducts become blocked or constricted. Because of this, it’s the most sensitive liver enzyme test for finding bile duct issues.

Since many types of liver issues can cause elevated levels of GGT in your blood, healthcare providers don’t use the test alone to diagnose conditions. Because of this, providers usually order GGT blood test alongside other liver function tests. It’s most often tested alongside an alkaline phosphatase (ALP) blood test, which measures another type of enzyme that’s found in your liver and bones.

Other names for a gamma-glutamyl transferase (GGT) blood test include:

• Gamma-glutamyl transpeptidase.
• GGTP.
• Gamma-GT.
• GTP.