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Beckman Coulter A32898 Access Thyroglobulin Antibody II Reagent (Access TgAb Reagent), 100 Determinations

$581.70

Brand: Beckman Coulter
Manufacturer SKU: A32898
Analyzer Type: Hematology Analayzer
Analyzer Series: Access Analyzer Series
Test Type: Antibody Test
Test Name: Anti-Thyroglobulin 2
Availability: Available on backorder SKU: A32898 Category:

Description

Beckman Coulter A32898 Access Thyroglobulin Antibody II Reagent (Access TgAb Reagent) Specifications:

  • Brand: Access
  • Manufacturer: Beckman Coulter A32898
  • Country of Origin: United States
  • Application: Reagent
  • For Use With: For use with Access Immunoassay Systems
  • Number of Tests: 100 Tests
  • Test Name: Anti-Thyroglobulin 2
  • Test Type: Antibody Test
INTENDED USE: Beckman Coulter A32898 Access Thyroglobulin Antibody II Reagent (Access TgAb Reagent)

The Beckman Coulter A32898 Access Thyroglobulin Antibody II assay is a paramagnetic particle, chemiluminescent immunoassay for the quantitative determination of thyroglobulin antibody levels in human serum and plasma using the Access Immunoassay Systems. The measurement of thyroid autoantibodies may aid in the diagnosis of Hashimoto’s disease, nontoxic goiter, and Graves’ disease.

SUMMARY AND EXPLANATION: Beckman Coulter A32898 Access Thyroglobulin Antibody II Reagent (Access TgAb Reagent)

Thyroglobulin is produced by the thyroid gland. It is a water soluble glycoprotein of approximately 660,000 Daltons. It is a major component of the thyroid follicular colloid and is present in small amounts in serum. The principal role of thyroglobulin is the storage and synthesis of thyroid hormones. The thyroid hormones 3, 5, 3′, 5′, – tetraiodothyronine (thyroxine, T4) and 3, 5, 3′, -triiodothyronine (T3) are synthesized from thyroglobulin.Thyroglobulin autoantibodies (TgAb) are often present in patients with autoimmune thyroid disease.

Approximately 10% of healthy individuals have TgAb at measurable levels. TgAb can be detected in 30% of patients with Graves’ disease and in 85% of patients with Hashimoto’s thyroiditis. However, elevated levels of autoantibodies to thyroid peroxidase (TPO autoantibodies) occur more frequently than high TgAb levels in these diseases.Sensitive TgAb methods are needed to identify patient sera that contain thyroglobulin autoantibodies that may interfere with serum thyroglobulin measurements.