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Beckman Coulter 33805 Access Total T4 Calibrator (S0-S5)


Analyzer Series: Access Analyzer Series
Brand: Beckman Coulter
Manufacturer SKU: 33805
Package Size: 6 x 4.0 mL
Test Name: Total T4
Analyzer Type: Hematology Analayzer
SKU: 33805 Category:


Beckman Coulter 33805 Access Total T4 Calibrator (Total T4 Test) Specifications:

Beckman Coulter 33805 Access Total T4 Calibrator (Total T4 Test) : INTENDED USE

The Access Total T4 calibrator are intended to calibrate the Access Total T4 assay for the quantitative determination of total thyroxine (T4) levels in human serum and plasma using the Access Immunoassay Systems.

Beckman Coulter 33805 Access Total T4 Calibrator (Total T4 Test) : SUMMARY AND EXPLANATION

Quantitative assay calibration is the process by which samples with known analyte concentrations (i.e., assay calibrators) are tested like patient samples to measure the response. The mathematical relationship between the measured responses and the known analyte concentrations establishes the calibration curve. This mathematical relationship, or calibration curve, is used to convert RLU (Relative Light Unit) measurements of patient samples to specific quantitative analyte concentrations.

What is a T4 test? (thyroxine test)
Beckman Coulter 33805 Access Total T4 Calibrator Total T4 Test | JIT4You Clinical Lab Consumables
Beckman Coulter 33805 Access Total T4 Calibrator Total T4 Test

A T4 (thyroxine test) test helps diagnose thyroid conditions.

Your thyroid is a small, butterfly-shaped gland located at the front of your lower neck, above your clavicle. It’s a part of your endocrine system. Your thyroid gland makes and releases thyroid hormones into your blood, which then travel to your organs to exert their effect.

Thyroxine, also known as T4, is the major type of hormone your thyroid releases. Too much or too little T4 can indicate thyroid disease.

Healthcare providers test T4 levels using blood tests. Thyroxine (T4) comes in two forms:

  • Bound T4: This form attaches to proteins, which prevents it from entering your body’s tissues.
  • Free T4: This form “freely” enters your body’s tissues where it’s needed.

Because of this, there are a few different tests that measure T4 levels. A blood test that measures both free and bound T4 is called a total T4 test. Other blood tests measure just free T4. Healthcare providers most often use a free T4 test to assess thyroid function because it’s more accurate than a total T4 test.

Your healthcare provider will most likely also order a TSH (thyroid-stimulating hormone) test alongside a T4 test. TSH is a hormone your pituitary gland makes. It stimulates your thyroid to produce T4 and T3 (triiodothyronine) hormones.

A TSH test is the best way to initially assess thyroid function. In fact, T4 tests more accurately reflect thyroid function when combined with a TSH test. Measuring T4 levels might not be necessary in all thyroid conditions.

Other names for a T4 test include:

  • Free thyroxine.
  • Total T4 concentration.
  • Thyroxine screen.
  • Free T4 concentration.
  • Free T4 index (FTI).
What is thyroxine (T4) and what does it do?

Thyroxine, also known as T4 and tetraiodothyronine, is the main hormone your thyroid gland releases into your bloodstream. Your thyroid also releases small amounts of triiodothyronine (T3). T4 and T3 work together and are commonly referred to as “thyroid hormone.”

Hormones are chemicals that coordinate different functions in your body by carrying messages through your blood to your organs, muscles and other tissues. These signals tell your body what to do and when to do it.

The T4 your thyroid releases is inactive, meaning it doesn’t affect your body’s cells. However, your liver and kidneys convert most of this thyroxine into triiodothyronine (T3), which is an active hormone that impacts the cells in your body.

Together, T4 and T3 play vital roles in regulating various bodily functions, such as:

  • Metabolic rate (the rate at which your body transforms the food you eat into energy).
  • Heart and digestive functions.
  • Muscle control.
  • Brain development.
  • Bone maintenance.
Synthetic thyroxine

Healthcare providers prescribe a synthetic form of thyroxine called levothyroxine to treat hypothyroidism (underactive thyroid). They can also prescribe it to treat some kinds of thyroid cancer alongside surgery and other treatments.