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OSR6196 Olympus LDL Cholesterol


Intended Use

Beckman Coulter OSR6196 Olympus LDL Cholesterol reagent, sometimes referred as a Low-Density Lipoprotein Cholesterol Reagent is used for the quantitative determination of LDL-Cholesterol concentrations in human serum and plasma on Beckman Coulter AU analyzers.

Brand: Beckman Coulter
Manufacturer SKU: OSR6196
Analyzer Type: Chemistry Analyzer
Analyzer Series: AU Analyzer Series
Test Type: Cardiac / Lipids
Test Name: Direct Low-Density Lipoprotein (LDL) Cholesterol
SKU: OSR6196 Category:


  • Manufacturer: Beckman Coulter OSR6196
  • Country of Origin: Japan
  • Application: Reagent
  • Number of Tests: 4 X 170 Tests
  • Storage Requirements: Requires Refrigeration
  • Test Name: Direct Low-Density Lipoprotein (LDL) Cholesterol
  • Test Type: Cardiac / Lipids / General Chemistry
  • UNSPSC Code: 41116004
  • Volume: 4 X 30 mL, 4 X 10 mL
Understanding LDL-Cholesterol

LDL-Cholesterol, also called Low-Density Lipoprotein Cholesterol, plays a significant role in causing coronary heart disease (CHD). In 1988, the National Cholesterol Education Program Adult Treatment Panel (NCEP-ATP) developed guidelines for diagnosing and treating hypercholesterolemia, with LDL-Cholesterol identified as the primary treatment target. The 2001 update of these guidelines (NCEP-ATP III) emphasized better risk identification and more aggressive cholesterol-lowering treatments.

Classification of LDL-Cholesterol Levels:

< 100 mg/dL: Optimal
100 – 129 mg/dL: Near optimal/above optimal
131 – 159 mg/dL: Borderline high
160 – 189 mg/dL: High
≥ 190 mg/dL: Very high


The LDL-Cholesterol test uses a two-reagent homogenous system. It consists of two phases:

In the first phase, a special detergent solubilizes cholesterol from non-LDL lipoprotein particles. This cholesterol is then consumed by various enzymes to produce a colorless end product.
In the second phase, another detergent in the second reagent releases cholesterol from LDL lipoproteins. This cholesterol reacts with enzymes and a chromogen system to produce a blue color complex. This complex is measured at 540/660nm, and the increase in absorbance directly correlates with the LDL-C concentration in the sample.


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