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OSR6195 Olympus HDL Cholesterol Reagent


Intended Use

Beckman Coulter OSR6195, Olympus HDL Cholesterol Reagent for the quantitative determination of HDL Cholesterol concentrations in human serum and plasma on Beckman Coulter AU analyzers.

Brand: Beckman Coulter
Manufacturer SKU: OSR6195
Analyzer Type: Chemistry Analyzer
Analyzer Series: AU Analyzer Series
Test Type: Cardiac / Lipids
Test Name: Direct High-Density Lipoprotein (HDL) Cholesterol
SKU: OSR6195 Category:


  • Manufacturer: Beckman Coulter OSR6195
  • Country of Origin: Japan
  • Application: Reagent
  • Number of Tests: 4 X 910 Test
  • Storage Requirements: Requires Refrigeration
  • Test Name: Direct High-Density Lipoprotein (HDL) Cholesterol
  • Test Type: Cardiac / Lipids / General Chemistry
  • UNSPSC Code: 41116004
  • Volume: 4 X 30 mL, 4 X 10 mL
Understanding HDL-C (HDL Cholesterol)

HDL-C, also known as High-Density Lipoprotein Cholesterol, plays a crucial role in reducing the risk of coronary artery disease by transporting cholesterol from peripheral tissues to the liver (reverse cholesterol transport), which helps prevent the formation of atheromatous plaques.

According to guidelines from The National Cholesterol Education Program Adult Treatment Panel 2 (NCEP ATP 2), it’s recommended to measure both HDL-Cholesterol and Total Cholesterol during initial screening for high cholesterol. In 2001, NCEP increased the threshold for high-risk medical decisions to HDL-C levels below 40 mg/dL.

Classification of HDL-C Levels:

< 40 mg/dL: Indicates a major risk factor for Coronary Heart Disease.
60 mg/dL: Considered a negative risk factor for Coronary Heart Disease.


The HDL-Cholesterol test is a two-reagent system designed to selectively measure HDL-Cholesterol in serum or plasma while excluding other lipoprotein particles. The test consists of two phases:

Free cholesterol in non-HDL lipoproteins is solubilized and consumed, resulting in a colorless end product.
A unique detergent selectively solubilizes HDL lipoproteins, allowing HDL cholesterol to react with cholesterol esterase, cholesterol oxidase, and a chromogen system, producing a blue color complex. This complex is measurable at 600/700nm, and the increase in absorbance directly corresponds to the HDL-C concentration in the sample.

OSR6195 Olympus HDL Cholesterol Reagent
OSR6195 Olympus HDL Cholesterol Reagent


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